The Mchaourab and Meiler labs hacked AF2 to show its ability to generate multiple protein shapes from a single sequence. These models revealed intermediate steps in an active transporter's shape changes. This early discovery suggests new ways to study protein dynamics, combining experimental and AI-based methods. Understanding protein dynamics could lead to designing drugs that target specific protein motions for better treatments. Connecting genomics to cellular behavior requires AI and protein experts to blend computational modeling, drug design, and experimentation.